Tilmicosin Phosphate (137330-13-3)
Mafotokozedwe Akatundu
● Tilmicosin phosphate ndi mankhwala a semi-synthetic macrolide.Ndi mankhwala atsopano okhudzana ndi nyama omwe ali ndi antibacterial spectrum.Tilmicosin phosphate ndi wamphamvu motsutsana ndi mabakiteriya a gram-negative ndi positive.Imakhalanso ndi mphamvu yoletsa kusiyanasiyana kwa mycoplasma ndi spirochetes.
● Tilmicosin phosphate amagwiritsidwa ntchito makamaka pa matenda opuma oyambitsidwa ndi Actinomyces pleuropneumoniae, Pasteurella hemolyticus, Pasteurella multocida, ndi ziweto ndi nkhuku.
| Zinthu | Zofotokozera | Zotsatira |
| Makhalidwe | White kapena pafupifupi woyera ufa | Pafupifupi ufa woyera |
| Chizindikiritso | Mayeso a IR: Amagwirizana ndi zomwe akunena | Zimagwirizana |
| Mayeso a HPLC: Amagwirizana ndi zomwe akunena | Zimagwirizana | |
| Zitsanzo zomwe ziyenera kuyesedwa zikuwonetsa momwe phosphate imachitikira. | Zimagwirizana | |
| Madzi | ≤7.0% | 3.0% |
| pH | - | 6.7 |
| Zosakaniza zogwirizana | ≤3% | 3% |
| Chiwerengero cha mankhwala onse ogwirizana≤10% | 5% | |
| Kuyesa (zouma maziko) | Timicosin ili ndi C46H80N2O13≥75% | 79.2% |
| Zomwe zili mu tilmicosin cis-isomers zili pakati pa 82. 0% ndi 88. 0% | 85. 0% | |
| Zomwe zili mu tilmicosin trans-isomers zili pakati pa 12. 0% ndi 18. 0% | 15.0% |
zokhudzana ndi mankhwala
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