Fructosyl-peptide Oxidase (FPOX)
Kufotokozera
Enzyme ndiyothandiza pakuzindikira fructosyl-peptide ndi fructosyl-L-amino acid.
Kapangidwe ka Chemical
Mfundo Yoti Muchite
Fructosyl-peptide + H2O + O2→ Peptide + Glucosone + H2O2
Kufotokozera
| Zinthu Zoyesa | Zofotokozera |
| Kufotokozera | White amorphous ufa, lyophilized |
| Zochita | ≥4U/mg |
| Chiyero(SDS-PAGE) | ≥90% |
| Catalase | ≤0.01% |
| ATPase | ≤0.005% |
| Glucose oxidase | ≤0.03% |
| Cholesterol oxidase | ≤0.003% |
Mayendedwe ndi kusunga
Mayendedwe: Wozungulira
Posungira:Sungani pa -20°C(Nthawi yayitali), 2-8°C (nthawi yochepa)
Kuyesedwanso kovomerezekaMoyo:2 chaka
Mbiri yachitukuko
Chimodzi mwazowonetsa zomwe zimagwiritsidwa ntchito pozindikira matenda a shuga ndi glycated hemoglobin (HbA1c).Kuyeza kwa HbA1c pogwiritsa ntchito ma enzyme ndikoyenera pokonza zitsanzo zambiri, ndipo ndikokwera mtengo.Chifukwa chake, kwa nthawi yayitali pakhala kuyitanidwa kwamphamvu kuchokera kwa azaumoyo kuti apange kuyesa kwa ma enzyme.Choncho, tinapanga kuyesa kwatsopano pogwiritsa ntchito "njira ya dipeptide".Mwachindunji, tidapeza "Fructosyl-peptide Oxidase" (FPOX) yomwe ingagwiritsidwe ntchito ngati enzyme pakuyesa uku.Izi zidatithandizira kuchita bwino pakukwaniritsa koyamba padziko lonse lapansi poyesa kuyesa kwa enzyme ya HbA1c."Njira ya dipeptide" iyi imagwiritsa ntchito Protease (Proteolytic enzyme) kuti iwononge HbA1c m'magazi, ndiyeno imayesa milingo ya dipeptides yopangidwa ndi saccharified yomwe imapangidwa pogwiritsa ntchito FPOX.Njirayi idalandiridwa bwino kwambiri chifukwa cha zabwino zake kukhala zosavuta, zotsika mtengo komanso zofulumira, ndipo choyezera cha HbA1c chogwiritsa ntchito FPOX tsopano chayamba kugwiritsidwa ntchito padziko lonse lapansi.
