Amoxicillin Trihydrate (61336-70-7)

Amoxicillin trihydrate, semisynthetic wide-spectrum penicillin, ali ndi antibacterial spectrum, mphamvu komanso ntchito ngati ampicillin.Amoxicillin trihydrate ndi hydrate yomwe ndi mtundu wa trihydrate wa amoxicillin;semisynthetic antibiotic, yomwe imagwiritsidwa ntchito yokha kapena kuphatikiza potaziyamu clavulanate (mu dzina la malonda Augmentin) pochiza matenda osiyanasiyana a bakiteriya.Imagwira ntchito ngati antibacterial mankhwala komanso antimicrobial agent.Lili ndi amoxicillin.Amoxicillin ndi maantibayotiki ambiri, semisynthetic aminopenicillin okhala ndi bactericidal.Amoxicillin amamanga ndi kuyimitsa puloteni yomanga penicillin (PBP) 1A yomwe ili mkati mwa khoma la cell ya bakiteriya.Kutsegula kwa ma PBP kumasokoneza kulumikizana kwa unyolo wa peptidoglycan kofunikira kuti ma cell a bakiteriya akhale olimba komanso olimba.Izi zimasokoneza kaphatikizidwe ka bakiteriya cell wall ndipo zimabweretsa kufooka kwa khoma la bakiteriya cell ndikuyambitsa cell lysis.

Amoxicillin anapezeka mu 1958 ndipo anayamba kugwiritsidwa ntchito pachipatala mu 1972. Amoxil inavomerezedwa kuti igwiritsidwe ntchito pachipatala ku United States mu 1974, ndi ku United Kingdom mu 1977. Ili pa List of Essential Medicines ya World Health Organization (WHO) ndi amodzi mwa maantibayotiki omwe amaperekedwa kwa ana.Amoxicillin amapezeka ngati mankhwala amtundu uliwonse.